Hayden Panettiere passed away due to toxic effects from several substances, including fentanyl, 4-ANPP, alprazolam, methocarbamol, and quetiapine, as stated by the Greenville County Coroner’s Office. Her death was classified as an accident.
Incident Details
On August 16, 2026, a 911 call was made at 1:51 PM concerning a cardiac arrest at 701 Easley Bridge Road in Greenville. First responders and Emergency Medical Services arrived promptly. Despite their efforts, Panettiere was pronounced dead at 2:32 PM.
The Greenville County Coroner’s Office, along with the Greenville City Police Department, conducted an investigation. Hayden Leslie Panettiere, aged 36 from California, was identified as the deceased. She was staying temporarily at the residence where she was found unresponsive.
Autopsy and Investigation
A Board Certified Forensic Pathologist performed an autopsy revealing no trauma that might have contributed to her death. The cause was determined as the toxic effects of the aforementioned substances.
The deceased star’s boyfriend, Brian Hickerson, and his brother Zach, were present at the scene. Hickerson provided a bag with medication Panettiere had been using to the authorities. Reports indicated that Hickerson showed emotion only after Panettiere was declared dead.
Response from Panettiere’s Representatives
Panettiere’s representatives criticized the spread of gossip related to her death. They emphasized respect for her memory and urged those with pertinent information to assist law enforcement instead of engaging in public speculation.
They also highlighted that important details about her death were not yet public, and those who knew Panettiere are working to ensure that the investigation reveals the complete truth and justice is achieved.

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