Drinking coffee on an empty stomach sparks debate, especially regarding its impact on cortisol levels and gut health. Social media has disseminated claims that coffee increases cortisol and harms the gut lining, yet some medical experts contest these views.
Impact on Cortisol and Gut Health
A TikTok post featured a medical professional asserting that coffee could elevate cortisol. Cortisol, produced by the adrenal glands above the kidneys, regulates stress responses, with fluctuations potentially affecting health.
“Coffee doesn’t seem to cause major problems when you drink it on an empty stomach,” remarked Dr. Asma Khapra, a gastroenterologist at GastroHealth in Fairfax, Virginia, to Fox News Digital.
Gastroenterologists challenge the notion that coffee on an empty stomach spikes cortisol. Cortisol naturally peaks in the morning, as outlined by the Cleveland Clinic, aligning with claims that observed “spikes” may reflect natural rhythms rather than coffee consequences.
Caffeine and Acid Reflux
Caffeine influences digestion, relaxing the muscular valve between the esophagus and stomach, which may increase heartburn risk by allowing stomach acid into the esophagus.
Both regular and decaf coffee stimulate stomach acid and gastrin release, and consuming coffee without food can induce nausea or abdominal discomfort, according to Dr. Douglas Weine, a gastroenterologist in New Jersey.
Effects of Caffeine on the Body
Caffeine is a stimulant, impacting the central nervous system to elevate blood pressure and heart rate, possibly triggering anxiety, heart palpitations, and sleep disturbances, as noted by Weine. Individuals vary in caffeine sensitivity.
The Cleveland Clinic confirms faster coffee absorption on an empty stomach, highlighting varying tolerance across individuals. While most healthy adults generally don’t experience adverse effects from coffee on an empty stomach, personal sensitivity plays a pivotal role.
Khapra mentioned, “it shouldn’t really cause too many GI symptoms.” She advises mindful consumption, avoiding excessive cream, milk, or sugar additives.
Sadie Chafe contributes to Fox News Digital’s Lifestyle team.

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